In addition, although many physicians prescribe AEDs for secondary prevention of PSS, it is uncertain which AEDs are most effective for the prevention of recurrence. Nevertheless, there are few reliable predictors of recurrent PSS. One observational study reported that about 50% of patients who received antiepileptic drugs (AEDs) after a first PSS episode had at least one recurrence during the follow-up period of 47 months. In one study, recurrent PSS developed in about 50% of patients who experienced late seizures but in only about 30% of patients with early seizures. The recurrence risk of PSS appears higher in the case of late seizures than in the case of early seizures. Recurrence of PSS is another clinical problem for stroke survivors. However, early seizures typically occur within the first few days after stroke, whereas late seizures have a peak within 6 to 12 months with a higher frequency of up to 66.7% of stroke survivors. In general, PSS is divided into two categories, early and late seizures, according to the timing of PSS, which is distinguished by the cutoff time-point of two weeks. In aged individuals, PSS accounts for 39%–45% of all seizures. Introduction Cerebrovascular disease is the most commonly identified cause of adult-onset epilepsy.Ĭardioembolic infarction, hemorrhagic stroke, and cortical lesions are most commonly associated with seizures, called post-stroke seizures (PSS).
Fa Premier League Manager 2002 Iso: Software Free Download on this page. Competing interests: The authors have declared that no competing interests exist. Funding: The authors received no specific funding for this work. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Data Availability: All relevant data are within the paper. Editor: Damir Janigro, Cleveland Clinic, UNITED STATES Received: ApAccepted: JPublished: AugCopyright: © 2015 Tanaka et al. (2015) Seizure Outcomes and Predictors of Recurrent Post-Stroke Seizure: A Retrospective Observational Cohort Study. Citation: Tanaka T, Yamagami H, Ihara M, Motoyama R, Fukuma K, Miyagi T, et al.
Factors significantly associated with PSS recurrence by log-rank analysis included previous PSS, valproic acid (VPA) monotherapy, polytherapy with antiepileptic drugs (AEDs), frontal cortical lesion, and higher modified Rankin Scale score at discharge (all p. PSS recurred in 31 patients (30%) during the follow-up. Results A total of 104 patients (71 men mean age, 72.1 ± 11.2 years) were analyzed.
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